Biotic Stress Resistance in Grapevines: A Review of Defense Mechanisms and Breeding Strategies  

Ding Ding IVY
Author    Correspondence author
Field Crop, 2025, Vol. 8, No.   
Received: 01 Jan., 1970    Accepted: 01 Jan., 1970    Published: 26 Aug., 2025
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Abstract
Studying the defense mechanisms and breeding strategies for grapevine resistance to biotic stresses is crucial for reducing pesticide use, enhancing yield stability, and promoting sustainable agricultural development. This study summarizes the primary defense mechanisms of grapevines against biotic stresses, including innate immune responses, specific immune responses, biochemical defenses, and physical barriers. It also reviews the application of traditional hybrid breeding, marker-assisted selection (MAS), genomic selection (GS), and CRISPR/Cas9 gene editing in improving grapevine resistance, and analyzes several successful case studies, such as the development of powdery mildew-resistant, phylloxera-resistant, and multi-resistant grapevine varieties. The findings illustrate the practical outcomes of resistance breeding in agriculture, emphasizing that grapevine resistance is regulated by a combination of biological mechanisms and environmental factors. Abiotic stresses (e.g., drought and heat) often interact with biotic stresses, further complicating resistance research. To address these challenges, future research directions include integrating multi-omics technologies, fostering international collaboration to share germplasm resources, and leveraging precision breeding technologies to enhance the efficiency of resistant variety development. This study provides comprehensive insights into grapevine resistance research and practices, offering significant implications for sustainable grape production and disease management.
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(The advance publishing of the abstract of this manuscript does not mean final published, the end result whether or not published will depend on the comments of peer reviewers and decision of our editorial board.)
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