Feature Review
Integrating Genomic Selection and Machine Learning for Predicting Maize Yield Under Drought 


Maize Genomics and Genetics, 2025, Vol. 16, No. 3
Received: 13 Apr., 2025 Accepted: 24 May, 2025 Published: 16 Jun., 2025
Drought is one of the most severe abiotic stresses faced by maize (Zea mays L.) production worldwide, which seriously restricts the stability of crop yield. Traditional breeding methods have limited adaptability in the context of complex climate change, and more efficient prediction methods are urgently needed. This study integrates genomic selection (GS) and machine learning (ML) methods, and uses large-scale genotype, phenotype and environmental data to improve the accuracy of maize yield prediction under drought conditions. This article systematically reviews the latest progress in genomic prediction of drought resistance traits, analyzes typical machine learning algorithms suitable for crop modeling, and proposes a strategy for integrating GS and ML and a hybrid model framework construction method. The feasibility and practicality of this method are verified through actual cases such as the CIMMYT drought-resistant maize project and Chinese maize hybrids. At the same time, the model's portability and robustness in different ecological environments are also evaluated. This study provides a theoretical basis and technical path for AI-driven precision breeding, which has important guiding significance for the cultivation of new maize stress-resistant varieties under drought conditions.
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