Shanjun Zhu

Institute of Life Science, Jiyang College of Zhejiang A&F University, Zhuji, 311800, Zhejiang, China
Author    Correspondence author
Cotton Genomics and Genetics, 2024, Vol. 15, No. 4   
Received: 11 Jul., 2024    Accepted: 18 Aug., 2024    Published: 26 Aug., 2025

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

This study aims to explore genetic and genomic strategies for enhancing pest resistance in cotton. By examining recent advancements in genome sequencing and editing technologies, the study seeks to identify key genetic traits and methodologies that can be leveraged to develop pest-resistant cotton varieties. The study highlights several significant discoveries in the field of pest resistance in cotton. Genome editing technologies, particularly CRISPR/Cas9, have shown immense potential in engineering durable resistance against insect pests and pathogens by altering effector-target interactions and knocking out host-susceptibility genes. Additionally, genome-wide association studies (GWAS) have identified specific loci and genes, such as GhnsLTPsA10, that play crucial roles in coordinating disease and insect resistance in cotton. The study also discusses the challenges posed by the rapid evolution of resistance in pests, such as the cotton bollworm, and the need for continuous monitoring and development of new resistance management strategies. The findings underscore the importance of integrating advanced genome sequencing and editing technologies in cotton breeding programs to enhance pest resistance. These genetic strategies not only promise to improve crop yields and reduce reliance on chemical insecticides but also contribute to sustainable agricultural practices. Future research should focus on fine-tuning these technologies and addressing the regulatory and social acceptance challenges associated with genetically modified crops.

Genome sequencing; Pest resistance; Cotton; Genetic breeding; Agricultural biotechnology